For eight consecutive days, the caregivers gathered their own saliva five times each day and held a diary of the changing times at which they gathered the saliva. They kept these saliva samples refrigerated until they may be shipped back to the laboratory. During the evenings of every of the eight times, interviewers from the Penn State Survey Research Middle called the participants and asked them about the daily stressors that they had encountered and also their mood.READ ON >> 9. Abilify Bristol-Myers Squibb and Otsuka collectively spent $107.9 million on advertising their schizophrenia and bipolar disorder treatment, Abilify, which accounted for 12.6 percent and 40 percent of BMS’s and Otsuka’s 2014 sales, respectively. The FDA approved the first generic versions of Abilify in April 2015. Regardless of the loss of patent safety, 8.3 million total prescriptions were written for Abilify in the first fifty % of 2015. Abilify is ranked No. 2 on the top 10 set of best-selling brand-name medicines for 2015. READ ON >> 10. Chantix Pfizer’s ad spending in 2014 on its cigarette smoking cessation agent Chantix increased 30 percent from 2013. In March 2015, the FDA updated Chantix’s label to reflect warnings about potential alcohol conversation and rare seizure risks.