Mizuki Nishino.

George R. Washko, M http://tadalafilo.org .D., M.M.Sc., Gary M. Hunninghake, M.D., M.P.H., Isis E. Fernandez, M.D., Mizuki Nishino, M.D., Yuka Okajima, M.D., Tsuneo Yamashiro, M.D., James C. Ross, M.S.D., David A. Lynch, M.D., John M. Brehm, M.D., M.P.H., Katherine P. Andriole, Ph.D., Alejandro A. Diaz, M.D., Ramin Khorasani, Ph.D., Katherine D’Aco, M.S., Frank C. Sciurba, M.D., Edwin K. Silverman, M.D., Ph.D., Hiroto Hatabu, M.D., Ph.D., and Ivan O. Rosas, M.D. For the COPDGene Investigators: Lung Volumes and Emphysema in Smokers with Interstitial Lung Abnormalities The relationship between contact with tobacco smoke and chronic obstructive pulmonary disease is well described.1 Two manifestations of COPD include emphysematous destruction of the lung parenchyma and elevated procedures of total lung capacity.3,4 The extent to which interstitial lung abnormalities may be associated with a reduced amount of emphysema and lower methods of total lung capability than anticipated on the basis of known smoking publicity is unclear.