Adverse Events Overall rates of adverse events were comparable in the clindamycin and TMP-SMX groupings . The most common adverse events in the clindamycin and TMP-SMX groupings had been diarrhea , nausea , vomiting , pruritus , and rash . Most adverse events were mild or moderate and resolved without sequelae. There were no treatment-associated significant adverse events . The rates of treatment discontinuation because of adverse events were identical in both groups .Leading an initiative such as this one, which is based on a solid platform of research, information technology, modern infrastructure, and nationwide collaboration in biomedical sciences, is totally aligned with the strategic strategy of the extensive research Institute of the MUHC. That a public-private consortium relating to the Canadian Institutes of Wellness Research and many large pharmaceutical companies is supporting this study and facilitating the transfer of understanding, from leads to actual patient treatments, underscores the need for this extensive research, notes Dr.